Signification of forkhead box A1 (FOXA1) expression in thyroid cancers
نویسندگان
چکیده
منابع مشابه
Lack of both androgen receptor and forkhead box A1 (FOXA1) expression is a poor prognostic factor in estrogen receptor-positive breast cancers
The present study aimed to examine the associations between androgen receptor (AR) and forkhead box A1 (FOXA1) and to investigate clinicopathological features and survival according to both biomarker status in estrogen receptor (ER)-positive breast cancers using in vitro study, patient cohort data, and the cBioPortal for Cancer Genomics and Kaplan-Meier Plotter websites. Experiments using T47D ...
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Forkhead box P3 (FOXP3) is well known as a key regulator of immune homeostasis. The abnormal expression of FOXP3 can contribute to features of several cancers including metastasis and invasion, and it has also been associated with prognosis of some cancers. However, little information is available for the expression of FOXP3 in hepatocellular carcinoma (HCC). In this study, we analyzed the expr...
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Forkhead box protein A1 (FOXA1) is a transcription factor; recent studies have reported that FOXA1 has an oncogenic or tumor suppressive role in human malignancies, and its expression is associated with the prognosis of patients with cancer. However, further studies are required to determine the clinical significance of FOXA1 and its role in colorectal cancer (CRC). In the present study, FOXA1 ...
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AIM Apocrine breast carcinoma often lacks estrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor type-2 (HER2) expression. Accordingly, development of a new treatment strategy is important for this type of cancer. The growth stimulus through the androgen receptor (AR) can be a candidate for targeted treatment. Therefore, we examined the factors related t...
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The forkhead protein, FOXA1, is a critical interacting partner of the nuclear hormone receptors, oestrogen receptor-α (ER) and androgen receptor (AR), which are major drivers of the two most common cancers, namely breast and prostate cancer. Over the past few years, progress has been made in our understanding of how FOXA1 influences nuclear receptor function, with both common and distinct roles...
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ژورنال
عنوان ژورنال: Journal of the Egyptian National Cancer Institute
سال: 2019
ISSN: 2589-0409
DOI: 10.1186/s43046-019-0011-2